APOMORPHINE
نویسندگان
چکیده
منابع مشابه
Apomorphine in Parkinsonian tremor.
Prostatic Reservoir of Gonococci L. Molin, M.D., and D. Danielsson, M.D. .. 767 Appendicitis in Infancy R. J. M. Love, F.R.C.S ................... 767 Perforated Diverticulitis A. P. Barabas, F.R.C.S . .................. 767 Apomorphine in Parkinsonian Tremor J. Braham, M.D., and others .............. 768 Hydroxyprolinuria C. E. Dent, F.R.C.P., F.R.S ................. 768 Viruses and Immunosupp...
متن کاملGenotoxic, neurotoxic and neuroprotective activities of apomorphine and its oxidized derivative 8-oxo-apomorphine.
Apomorphine is a dopamine receptor agonist proposed to be a neuroprotective agent in the treatment of patients with Parkinson's disease. Both in vivo and in vitro studies have shown that apomorphine displays both antioxidant and pro-oxidant actions, and might have either neuroprotective or neurotoxic effects on the central nervous system. Some of the neurotoxic effects of apomorphine are mediat...
متن کاملThe apomorphine test in parkinsonian syndromes.
The dopamine receptor agonist apomorphine has been used successfully to treat on-off swings in Parkinson's disease. Its value as a predictor of dopa responsiveness in idiopathic Parkinson's disease (IPD) was assessed and its potential role in differentiating IPD from the Parkinsonian plus syndromes (PPS) of multisystem atrophy, progressive supranuclear palsy and olivopontocerebellar atrophy was...
متن کاملBiphasic effect of apomorphine on rodent motility.
The dopaminergic (DA) system has been implicated in a number of neurological and psychiatric disorders. In studying neurotransmitter systems such as the DA system in the laboratory animal, behavioural studies are commonly employed. Since behaviour is a sum total of a variety of internal and external excitations and inhibitions. in such studies it it necessary to use a chemical probe which speci...
متن کاملOxidative behaviour of apomorphine and its metabolites.
The metabolism of apomorphine is quite complex due to interactions with proteins and other tissue components that affect its pharmacokinetic profile. The electrochemical oxidation mechanism of apomorphine and of some synthesised apomorphine derivatives was studied. It was found to be related to the reaction of o-diphenol and tertiary amine groups and strongly dependent on pH.
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1978
ISSN: 0007-0912
DOI: 10.1093/bja/50.3.308